The NYU Covid Closures (CoClo) Study aimed to understand the impact that the COVID-19 pandemic has had on the closures of food retail stores, restaurants, and produce vendors in six NYC neighborhoods. After selection of 6 lower- and higher-resourced neighborhoods based on characteristics reported in the NYC Neighborhood Health Atlas, restaurants and food retail stores for each neighborhood were ascertained by the most up-to-date sources of information. To assess COVID-19 closures for restaurants, food retails stores, and produce vendors, the study team followed a rigorous procedure of checks: internet, call, and in-person. This study found that lower-resourced neighborhoods had fewer food outlets, restaurants are more likely to close than food retail stores, and that there were higher proportions of COVID-19 food outlet closures in Chinese neighborhoods compared to other neighborhoods. In conclusion, food outlets in ethnically Chinese neighborhoods have faced a disproportionate impact during COVID-19. Restaurants and produce vendors were particularly socioeconomically impacted.